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Program Suspension For Cats (Box Of 6)

R410.00 R369.00

Program is the cornerstone of the successful flea control program. It prevents development of breeding flea populations therefore preventing recognizable infestations. It also effectively targets 85% of existing infestations comprised of eggs and larvae.

The active ingredient that controls fleas in Program is lufenuron, a benzoylphenyl urea (BPU) derivative. BPU’s have been tested since the 1970s for their activity on insects. All BPU’s, including lufenuron, are classified as Insect Development Inhibitors (IDI’s).

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Program inhibits chitin synthesis, polymerization and deposition within the flea. Chitin is composed of polymers (links of molecules in a chain) of amino sugars and functions in many areas of flea development:

  • Chitin appears in the egg case to prevent desiccation (loss of water/fluid).
  • Flea larvae inside the egg possess an “egg tooth” composed of chitin that is used during hatching.
  • The larval exoskeleton contains chitin for structural integrity and to prevent desiccation.
  • The exoskeleton of the adult flea contains chitin that provides sites for muscle attachment and protection against pathogens, mechanical rupture and desiccation. Chitin comprises 25-
  • 50% of a flea’s dry weight.

By interfering with chitin deposition, lufenuron disrupts hatching and larval moults. Studies show that faeces from adult fleas feeding on treated animals contains Program and is passed through to the environment. This flea faeces containing Program proved lethal to existing larvae that ingested them, making Program 100% effective in preventing the development of the egg and larval stage of the flea life cycle. It is this specific mode of action that makes Program such an effective flea control method, as the adults present in an infestation make up only 5% of the total population. With eggs comprising 50%, larvae 35% and pupae 10%.

The pet owner feeds Program to the pet with a full meal. After ingestion, lufenuron is completely absorbed from the stomach within 3 hours. Peak absorption is attained within 6-12 hours. It is deposited into the body fat of the pet and within 24 hours is 95% effective. 48 Hours after the oral dose it is 100% effective and remains at this level as long as subsequent monthly doses are given with a full meal.

Being highly lipophilic (having an affinity for fat), Program distributes in the adipose (fatty) tissues, then releases slowly back into the bloodstream at therapeutic levels for at least 32 days. During a blood meal (which the flea must take in order to reproduce) the female flea ingests Program, which is subsequently transferred to her eggs and is deposited in her faeces.

Egg hatching is prevented when the flea’s chitin-containing “egg tooth” and exoskeleton fail to develop. Another aspect of Program’s action is its effect on fleas already in the environment. Larvae that may hatch from treated eggs (possibly due to the movement or feeding of existing larvae) die during the first larval moult due to disruption in their chitin formation. Existing larvae within the environment, or from eggs that were laid before the pet was put on Program, feed upon the flea faeces containing Program, and also die.

When recommending Program, veterinarians will discuss certain issues with their clients, and develop an integrated flea control program that will meet their needs. The use of Program for flea control should be conducted under the instructions and supervision of your veterinarian, and should take into account the following factors:

  • The life cycle of the flea.
  • The level of flea infestation.
  • The desired speed of control.

The length of the flea life cycle can vary tremendously based on temperature, humidity and time spent in the pupael stage. Under ideal conditions of 24° Celsius and 78% humidity, the cycle is completed in as little as 14 days. Without stimulation, fleas may remain inside the cocoon for 4-6 months or more before they emerge. It is important to realize that if fleas are seen by the owner due to a delayed pupael hatch, that this isn’t a break in efficacy. These newly hatched fleas were deposited in the environment before the pet was on Program and have remained dormant. Rest assured that once these fleas are exposed to Program they will not be able to reproduce.

Program administration breaks the flea life cycle by inhibiting egg and larval development. However, pre-existing flea populations continue to develop and emerge after treatment with Program begins. Based on clinical studies, this continued emergence of pre-existing fleas is most significant during the first 30 to 60 days.

If a flea feeds on an untreated dog or cat for three days, it regains the ability to produce viable eggs. Therefore, it’s critical that all dogs and cats in a household be treated with Program if fleas are to be effectively controlled.

Used alone, Program can effectively bring an existing flea infestation under control. However, some owners are not willing to have their pet suffer from fleas for as long as it takes them to die off on their own. To ensure owner satisfaction, conventional flea control products may be used in conjunction with Program for the first 4-6 weeks to establish adult flea control in an existing infestation where Program is introduced. Although every household situation cannot be anticipated, the following scenarios are those typically encountered by veterinarians.

No Flea Infestation Situation

The pet owner and veterinarian have seen no evidence of fleas.


  • Program should be administered to all pets in the home prior to the beginning of flea season, or preferably year-round. Your veterinarian will be able to advise you of the correct date to begin treatment with Program.
  • On-animal adulticides should be used only if the pet is exposed to adult fleas outside its normal environment.
  • Program administration with a full meal should continue for the entire flea season.

Mild Flea Infestation Situation

A flea infestation is considered mild if there is no evidence of flea allergy or flea bite dermatitis or if only small numbers of live fleas are found on the pet.


  • Program should be administered to all pets in the home. # A topical adulticide should be used to control pre-existing fleas emerging in the environment.
  • Vacuuming carpet and upholstery to stimulate fleas to emerge from cocoons and remove some from the environment. The pet’s bedding should be washed.
  • Once the flea problem is under control (usually within 4-6 weeks), the on-animal product can be discontinued.
  • Program administration with a full meal should continue for the entire flea season.

Severe Flea Infestation Situation

A flea infestation is considered severe if the pet has evidence of flea allergy or flea bite dermatitis, if large numbers of live fleas are found on the pet or if fleas are biting people in the home.


Program should be given to all pets in the home.

  • An on-animal adulticide should be used to control emerging fleas.
  • Vacuuming carpets and upholstery stimulates fleas to emerge from cocoons and removes some from the environment. The pet’s bedding should be washed.
  • Conventional premise adulticides, with IGR’s, are used to kill pre-existing stages in the environment.
  • Even after environmental treatment, pre-existing pupae may continue to emerge. This occurrence is called the “Pupael Window” effect and is discussed in the section on FLEA BIOLOGY. In the most severe cases, a second application of environmental spray may be used according to label directions to curb extremely large emerging pupael populations.
  • Once the flea infestation is under control (usually within 3 months), the on-animal product may be discontinued.
  • Program administration with a full meal should continue for the entire flea season.

In all three of these situations – no adults are killed as a result of administering Program. It is critical that owners understand that Program inhibits the future development of the eggs and larvae (85% of the population) to prevent an infestation but does not kill the 5% adults present.

The inconvenience of subsequent messy home and on-animal treatments is prevented by the regular administration of Program to pets by preventing fleas from developing in the home.

Additional information

Weight 0.45 kg


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