It is efficacyious against ticks, fleas and mites. Fluralaner is for systemic use and belongs to the class of isoxazoline-substituted benzamide derivatives. Fluralaner is an inhibitor of parts of the arthropod nervous system. The mode of action of fluralaner is the antagonistonism of the ligand-gated chloride channels (gamma-amenobuyotic acid (GABA)- receptor and glutamate-receptor).

Bravecto Spot-On should be administered in accordance with the following table corresponding to dose of between 25 and 56mg fluralaner/kg body weight in dogs and between 40 and 94mg fluralaner/kg body weight in cats within one weight band.